Noopept has held the throne of the strongest Nootropic since its very birth. Synthesized in Russia, Noopept is often confused as a Racetam, even though it is technically NOT a Racetam molecule. Noopept is extremely popular both due to part of its potency and because of the body of scientific backing for its ability to enhance memory and the ability to protect existing neurons in the brain (neuroprotection). Noopept shares a similar structure as Aniracetam and Piracetam, however, Noopept’s mechanism of absorption and means of being metabolized are undergone in a different manner. Another critical difference between Noopept and other Nootropics is the MUCH smaller dose required. Noopept’s amazing potency allows for a much smaller dosage needed. In essence, Noopept has been thought of by many as a buffed up version of Piracetam. This being said, Piracetam leads the front for Nootropics by proverbially paving the way for other compounds to be discovered, researched, and further modern medicine to more properly treat various cognitive ailments. The traction that nootropics have gained may be credited to Piracetam’s discovery and research.

What are some of Noopept’s Benefits?

Just why is this Nootropic earned its place as a staple of most Nootropic stacks? To find more info just go through the following benefits it possesses that has earned it that very place:

Improving Memory and Preventing Cognitive Decline

Noopept has been shown to increase Neurotrophic factors with a SINGLE dose. Neurotrophic factors are a family of proteins that are responsible for the growth and survival of developing neurons and the maintenance of mature neurons; in English, this means it’ll help you gain new brain cells as well as keep the existing ones alive. A few of these Neurotrophic factors are BDNF, NGF, and mRNA. With a surplus of new brain cells coming in and old ones living longer due to being less vulnerable to excitotoxins, cognitive functioning tends to thrive under these conditions. The Neurotrophic factors can be thought of as the direct mechanism for enhanced memory and cognitive decline. Noopept also exerts a “cholinosensitizing” effect, which is a fancy way of saying Noopept makes Acetylcholine more effective and sensitive. Acetylcholine is a brain chemical with a major role in the ability to learn and remember. This sensitization to Acetylcholine is a perfect example of why stacking a choline source such as Alpha-GPC or another Choline source would be deemed wise [1][3]. Having adequate levels of Acetylcholine is critical for having a decent memory now, and for keeping your brain mentally sharp as you age. If you suspect you have an acetylcholine deficiency, here are the symptoms, the causes, and how to boost your levels naturally.

Neuroprotection

Our brains tend to absorb a lot of abuse on a daily basis. Factors such as alcohol, smoking, various pathogens, dietary inadequacy, oxidants, and a plethora of various cognitive slowing factors batter our brains on a daily basis. The brain does not have the ability to experience pain because there are no pain receptors in the brain itself. I know what you’re thinking, “I’ve had headaches that beg to differ, my friend.” That pain you feel during a headache is the meninges (coverings around the brain) and periosteum (coverings on the bones). The point is, that the various trauma our brains undergo on a daily basis cannot be felt. The brain has no means of telling us we’re misbehaving. That’s where Noopept comes into play. The neuroprotective effect of this Nootropic in healthy subjects has been shown to be quite pronounced during various states of cognitive trauma, including oxidative stress, concussions, physical trauma, and other cognitive hindering instances.

Some examples of Neuroprotection in studies

Over the course of 56 days of treatment in persons with cerebrovascular insufficiency, Noopept at a 20mg dosage is more effective than a 1200mg dose of Piracetam in improving global MMSE scores and was effective in persons with post-traumatic cerebral insufficiency.[1]. Moreover, Noopept’s Neuroprotective benefits are seemingly more effective than Piracetam on a gram for gram basis. Moreover, Noopept shows a neuroprotective effect on not only healthy individuals but is exceptionally effective when some degree of cognitive damage is present (stroke victims, brain ischemia, brain fog, neurotoxicity, etc.) A side by side comparison of Noopept and Piracetam, reveals that Noopept surpasses Piracetam and requires a much smaller dosage to do so. Where Piracetam failed to attenuate the neurocytotoxic (brain-cell killing) effect of glutamate (more commonly known as MSG, found in a lot of packaged foods), Noopept significantly succeeds over Piracetam at protecting the brain against this extremely common substance. Piracetam was only effective in those with vascular disease and not trauma patients. Noopept improved brain blood flow and prevented brain toxins, such as excess calcium and glutamate via its antioxidant and anti-inflammation mechanisms.

Restoration of Memory and other Cognitive Functions after Brain Injury

Noopept has shown to be an advantageous Nootropic for restoring cognitive function back to optimal levels. The restorative effects are said to take place after brain injury, ischemia, and prenatal damage and have been noted to show improvements in central nervous system functioning in patients while restoring damaged cells and often correlated damaged receptor sites commonly noted in most Alzheimer’s patients. As stated above, Noopept is a neuroprotective and an anti-oxidant in the nervous system and the brain; through this mechanism, restoration of cognitive functioning such as memory, learning, and lifted brain-fog can be alleviated. The applications of Noopept extend past just treatment of Alzheimer’s patients. Noopept is treated for individuals with brain damage from physical impact, alcoholics who have destroyed brain cells through alcohol abuse, and the like. The assault our brain undergoes on a daily basis can be attenuated with the increased expression of Neurotrophic factors. Our brains are quite durable. They put up with a wide array of factors that attempt to damage them. BDNF and other Neurotrophic factors are the heroes that fight against these factors of the determinant.

Noopept’s Other Benefits:

• Attenuating depression
• Anti-anxiety benefits
• Learned-helplessness treatment
• Psychostimulatory effects